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DeCS
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Descriptor English:
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Flap Endonucleases
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Descriptor Spanish:
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Endonucleasas de ADN Solapado
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Descriptor Portuguese:
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Endonucleases Flap
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Synonyms English:
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Endonuclease-1, Flap
Endonucleases, Flap
FEN-1
Fen1 Protein
Flap Endonuclease 1
Flap Endonuclease-1
Nuclease, RTH-1
RAD2 Homolog 1 Nuclease
RAD2 Homolog-1 Nuclease
RTH 1 Nuclease
RTH-1 Nuclease
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Tree Number:
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D08.811.277.352.355.325.350
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Definition English:
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Endonucleases that remove 5' DNA sequences from a DNA structure called a DNA flap. The DNA flap structure occurs in double-stranded DNA containing a single-stranded break where the 5' portion of the downstream strand is too long and overlaps the 3' end of the upstream strand. Flap endonucleases cleave the downstream strand of the overlap flap structure precisely after the first base-paired nucleotide, creating a ligatable nick. |
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History Note English:
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2004; use FLAP ENDONUCLEASES (NM) 1994-2003; for FEN1 PROTEIN use EXODEOXYRIBONUCLEASE V 1997-2003; for RTH-1 NUCLEASE use EXODEOXYRIBONUCLEASE V 1996-2003
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Allowable Qualifiers English:
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Record Number:
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38146
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Unique Identifier:
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D045585
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Occurrence in VHL:
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Similar:
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DeCS
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